Adapin

 

            Adapin is the brand name for a series of drugs known as Doxepin. It is an antidepressant and is used in a wide range of treatments.

            This class of drug (Doxepin hydrochloride) is known as psychotherapeutic. Placed in a class of other drugs knows as dibenzoxepin tricyclic compounds. Tricyclic are basically anti-depressants used for treating anxiety.

            Sometimes the drug can simply be used for anxiety disorders, such as chronic skin disorders, peptic ulcer disease, itching, panic disorders, postprandial hypoglycemia, and posttraumatic stress disorder (PTSD).

            This is such a useful drug; it has been used in the treatment of many other fields. Sleep disorders, stopping people from smoking and even to decrease urination at night. Other fields that have seen Adapin used widely are arthritis and even for pain in cancer patients.

Warning precautions

           
            Happily the amount of habit forming associated with Adapin, is zero. Some of these doxepin compounds have caused problems, and patients have had trouble if they stop taking their medication. Especially if they have been used to it over a long period of time.

            There is a great deal of warning for pregnant women, and they must seek advice. Also caution must be taken with women planning a family in the future. As with women who are breast feeding.

            Smoking and drinking alcohol are never advised with any medication.
           
            It is certainly not suitable for children under the age of 12. For the over sixties, Adapin is only given in small doses and under close supervision, as the results from side effects could be a problem, especially from falling.

            Doctors will only prescribe the drug, if your medical history clears you for this class of drug, and would not be given if for example, you suffer heart problems. Other area of concern would be diabetes, glaucoma, epilepsy, enlarged prostate gland, an overactive thyroid, or liver disease.

            Medical professionals are never happy administering other drugs if you are undergoing medical tests, or booked into surgery in the near future.

            Overdose!

            If there is the slightest concern that someone has overdosed on this drug, they must seek medical help. The symptoms start with agitation, breathing problems, and delirium, and can result in going into shock, coma and can be fatal.

            When the patient is conscious, the doxepin is quickly absorbed in the body, but it still has to be washed out of the body with a gastric lavage. Care should be taken to prevent pulmonary aspiration, in the patient. Activated Charcoal can be used with gastric lavage and a saline drip for 24 hours, at least. Once this is in place, the patient will need constant monitoring with EKG machines. There is a danger of the person slipping back into a coma, so there may be a need for assisted ventilation.

            How to Take

 

            Adapin must be taken with food, and it is never a good idea to take them on an empty stomach. So take with meals.

            The Side Effect

 

            Some patients can suffer side effects from taking Adapin over a period of time. Any side effects must be reported to the Doctor, as this could have more worrying consequences. Things to watch for are from constipation and a dry mouth, to low blood pressure, drowsiness and blurred vision. These are still common problems, and if checked in time, can be remedied. Other, rarer problems can be from allergies, and an increased appetite, to ringing in the ears and palpitations. 

            Since it can cause drowsiness in some patients, Doctors advice against driving and operating heavy and dangerous machinery.

            Patients who are put on this drug will probably be suffering from depression. So it is very important to watch them carefully, especially in the early days. To make sure they are at low risk, only a small dosage should be given from the start. The risk of suicide is an obvious danger with these patients, so there should be no access to large doses of doxepin until Doctors are certain of stability.

            Some people can feel the effects of taking the drug in a few days, but most notice it having a real effect over a couple of weeks.

            How this drug works, is not exactly know, and a great deal of mystery still surrounds it. What they do know is that it does not stimulate the central nervous system, nor does it act as a monoamine oxidase inhibitor. They influence adrenergic (nerve fibres that release noradrenaline as a neurotransmitter) activity at the synapses.

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