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Generic name: fluticasone Brand name: Flonase What is fluticasone propionate? Fluticasone propionate is a synthetic corticosteroid. It is a white to off-white powder. Fluticasone propionate does not dissolve in water. It will dissolve completely in either dimethylsulfoxide or dimethylformamide. If the powder is put in ethanol, then about 95 % of the powder will dissolve in the ethanol. In what form does the pharmacist sell fluticasone propionate? When put into suspension, then fulticasone can be used as a nasal spray. Flonase is one such nasal spray. Flonase comes with a spray pump. What health problem is corrected by the use of Flonase? Flonase is an anti-inflammatory drug. Flonase treats the inflammation of the lung passages that can lead to an asthma attack.
How to take Flonase: Before a patient can use the Flonase pump, that pump must be primed. The priming of the Flonase pump, a requirement for the first use of that pump, must be repeated, if the pump has not been used again for more than five days. Once the pump of the Flonase container has been primed, then the patient needs one does (one spray in each nostril) every day. Each spray of Flonase allows the nostril to take in 50 mcg of fluticasone propionate. The total weight of each sprayed suspension comes to 100mg. A 10 g bottle of Flonase will deliver a total of 120 sprays, or 60 days worth of sprays. Side effects of Flonase: Repeated use of Flonase can cause a patient to develop candida albicans. If a doctor finds that a patient has developed candida albicans, then the doctor should tell the patient to stop using the Flonase. Other side effects can develop, if a patient is changing from a systemic corticosteroid to a local corticosteroid. Some patients respond to such a change with withdrawal symptoms, such as joint or muscle pain, lassitude and depression. Precautions or Warnings regarding Flonase: Do not use Flonase if you have recently had nasal surgery. Do not use Flonase if you are pregnant. Do not take Flonase with a cytochrome P450 inhibitor, such as ritamair. What to do if you get an overdose of Flonase: If your body is exposed to an excessive amount of Flonase, then contact your physician right away. (see notes below) What to do if you miss a dose of Flonase: If you miss a dose of Flonase, then administer the prescribed dose as soon as possible. If you are close to the time for the administration of a repeat dose, then wait the interval of time that will bring you to the appointed time for the next dose. How to store Flonase: Store Flonase at room temperature. Keep it away from heat and light. Special information regarding Flonase: Flonase is a substrate of the enzyme cytochrome P-450. Cytochrome P-450 is found in the liver. Research scientists have established a link between the presence of cytochrome P-450 and damage to human chromosomes. Some evidence suggests that this damage can be greater in the presence of certain carcinogens. How to use the above information when talking with your physician: The recommended dose of Flonase assumes that the patient has a liver that functions normally. If the patient has liver problems, then the physician should know about those problems. The recommended dose of Flonase assumes that the patient has no large number of fast growing cells that could undergo DNA damage. If a woman is pregnant, she should consult with her doctor, before taking Flonase. The recommended dose of Flonase assumes that the cytochrome P-450 will not act an increased rate, due to the presence of carcinogens. If a patient is a heavy smoker, and is thus exposed to large doses of benzopyrene, then the patient should check with the doctor before starting to use Flonase. Urban air also has a high concentration of benzopyrene. Patients living in an urban area might consult with a doctor before using Flonase.
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Ethinyl Estradiol and Norelgestramin |
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Abacavir |
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