Role Of Cymbalta In Fibromyalgia

To understand role of cymbalta in fibromyalgia, we first need to know some facts about cymbalta and fibromyalgia.

Some Facts About Fibromyalgia

What Is Fibromyalgia? Fibromyalgia is a common chronic condition.

Symptoms Of Fibromyalgia: There is a constellation of symptoms present in fibromyalgia, which are as follows; extensive musculoskeletal pain, fatigue, and multiple tender points. The tenderness is present in the localized areas present in the neck, spine, shoulder and hips.

Other Symptoms Of Fibromyalgia: The people who are suffering from fibromyalgia also experience sleep disturbances, morning stiffness, irritable bowel syndrome, anxiety and other symptoms.

Gender Affected: The gender suffering most from fibromyalgia are women than men.

Some Facts About Cymbalta

Type: Cymbalta is an antidepressant drug.

Generic Name: The generic name of the drug is duloxetine hydrochloride.

Pronunciation: The name of the drug is pronounced as sim-BAWL-tuh.

Class Of Drug: Cymbalta is a dual-reuptake inhibitor of serotonin and norepinephrine.

What Does Cymbalta Targets? Cymbalta targets two chemical messengers in the body, serotonin and norepinephrine, which are believed to play a role in both depression and pain perception.

Effective Dosage: Cymbalta when given 60 mg once or twice daily, significantly reduces the pain in more than half of women who are treated for fibromyalgia, with and without major depression.

Study Conducted To Determine The Role Of Cymbalta In Fibromyalgia

General Background About Fibromyalgia: On the basis of the data collected, fibromyalgia takes its toll between three and six percent of the population. Fibromyalgia mainly affects women and as a symptom complex, it causes headaches, fatigue and other related complications. Why fibromyalgia occurs is still not clearly known, but as elaborated by the studies, they are linked to abnormal amounts of the chemicals serotonin and norepinephrine, which are also associated with depression and pain perception. The researchers thought that the drugs that are used for depression can be used for the patients who are suffering from fibromyalgia, because the patients who were suffering from fibromyalgia also had problems with depression.

Purpose Of The Study: The basis of conducting the research was that the researchers wanted to know whether the drug, Cymbalta, which is an antidepressant drug, whose generic name is duloxetine can help the patients who are suffering from fibromyalgia.

Planning Out The Study: In order to conduct the study the researchers enrolled about 200 patients from around the country and after that the patients were divided into two equal groups. The researchers planned that they would give Cymbalta to one group for about 12 weeks and the other group will be given a sugar pill as a placebo for about the same amount of time.

Filling Out Of Questionnaires By Participants: The participants completed the questionnaires, which was based on the amount of pain and discomfort that the disease caused them at the beginning of the study. After that they filled out the questionnaire at the end of each of the first two weeks, as well as every second week for the remaining 12 weeks of the study. Along side measuring the pain level, they also checked the participants for depression.

Results Of The Study: The results of the study were quite astonishing for the researchers. They found out that women who took Cymbalta had significantly less pain and discomfort than those who took the placebo. The men who only made about 11 percent of the participants in the study showed that there were no effects from taking the medication compared to a placebo. The ratio of the men in the study was low because fibromyalgia occurs four times more in women than in men. The women who were taking the drug had greatly decreased levels of pain after taking the drug for about the 12-week period of time. Hence this study proved really beneficial to find the relationship between Fibromyalgia and Cymbalta.

How Can It Change The Lives Of People: If you are a person suffering from fibromyalgia, then you can very clearly understand as to how your life is miserable with this disease and how much you want to get rid of it from your life and you know that there are people out there working for you to come up with ways to cure this condition whose cause is not yet known. Thus the drug, Cymbalta, can greatly reduce the pain in individuals suffering from fibromyalgia thus enhancing their quality of lives and taking the misery out so they could lead their lives to the max. In other words, we can call this drug, a miracle drug, which can bring a new dawn in the lives of the sufferers.

Drawback Of The Research: Since this research was conducted only for about 12 weeks, it is not known as to how the drug would benefit if it were taken for a longer period of time in patients suffering from fibromyalgia.

Views Of Doctors On Fibromyalgia-Cymbalta Relationship: Dr. Lesley M. Arnold, M.D. from University of Cincinnati, College of Medicine, Cincinnati, Ohio, said that “Cymbalta significantly improved these patients' quality of life and overall functioning, as measured by quality of life and disability scales."

The designer of the study mentioned above, Dr. Raskin said that, “Duloxetine showed a direct effect of 75% to 85% improvement in pain reduction. About sixty milligrams a day was the effective dose and that is similar to what we have seen with duloxetine for peripheral neuropathic diabetic pain."

In his other words he added, "Very notably, duloxetine showed an effect on relief of the 'tender point' pain of fibromyalgia, which is one of the diagnostic criteria for the condition." He further continued that "It is a truly objective finding among studies in which findings are often rather subjective. Here you see changes in a standard and objective measure of pain. This is really quite a unique finding."

Bottom Line for cymbalta and fibromyalgia relationship

This is a remarkable research in treating the problems of fibromyalgia. Now this drug, Cymbalta, ensures that people who are going through a miserable life of suffering fibromyalgia will have a break in their symptoms and they will be able to lead a better quality of life. In the above article, we have thoroughly discussed a lot of different aspects supporting the relationship of fibromyalgia and Cymbalta. We hope that those of you who are going through this problem will come to read this article and will open the doors of betterment in your life.

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